Friday, 9 December 11:00am – 12:00pm

This seminar will be delivered in Chemistry Lecture Theatre 4 and Online Zoom Please email chemistry.researchsupport@sydney.edu.au for zoom link and password.

Speaker: Tom Muir; Department of Chemistry, Princeton University

Host: Prof. Rich Payne

Title: Illuminating chromatin: chemical biology tools light the way

Abstract: The field of epigenetics has exploded over the last two decades revealing an astonishing level of complexity in the way genetic information is stored and accessed in eukaryotes. This expansion of knowledge, very much ongoing, has been made possible by the availability of ever more sensitive and precise molecular tools, including those grounded in the fields of peptide and protein chemistry. In this presentation, I will discuss the development of various chemical biology approaches designed to explore spatiotemporal aspects of epigenetic regulation. These methods are helping to expose the remarkable nuances (and vulnerabilities) of epigenetic control mechanisms, providing insights into how these processes become corrupted in cancer.