HDR Seminar: Ms Amy Bowyer; The University of Sydney – School of Chemistry HDR Seminar: Ms Amy Bowyer; The University of Sydney – School of Chemistry

HDR Seminar: Ms Amy Bowyer; The University of Sydney

Monday, 8 August 4:00pm – 5:00pm

This seminar will be delivered in Chemisty Lecture Theatre 4 and Zoom online. Please email chemistry.researchsupport@sydney.edu.au for zoom link and password.

Speaker: Ms Amy Bowyer; The University of Sydney

Supervisor: Prof. Liz New

Title: Fluorescence sensing approaches to environmental heavy metal detection

Abstract: Heavy metals, such as lead, mercury and cadmium, are extremely toxic; they cause serious adverse human health effects at micromolar blood levels. As a result, it is important to monitor heavy metal ion levels in water sources to minimise human exposure. At present, heavy metal ion analysis is predominantly conducted in laboratory facilities with expensive equipment, making on-site testing unfeasible. Optical sensors, such as small molecule fluorescent probes, have the advantage of requiring less expensive machinery and analytical expertise, while retaining high sensitivity.

This seminar will detail two fluorescence-based approaches to environmental toxic metal detection. In the first approach, a novel BODIPY-based fluorescent sensor was synthesised and evaluated as a selective probe for Pb2+. Selectivity was achieved using a dipicolinate chelating group that produced a ratiometric, turn-on response to Pb2+ in a completely aqueous solvent. This marks the first time that a chelating group from a known selective Pb2+ probe has been applied to a different fluorescent scaffold to retain Pb2+ selectivity. In the second approach, cross-reactive sensing arrays consisting of a minimal number of simple coumarin sensors were used to accurately discriminate between toxic and essential metal ions in a variety of sample environments, including tap water, pond water and dam water.


Aug 08 2022


4:00 am - 5:00 pm


Chemistry Lecture Theatre 4
Level 2, School of Chemistry

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