Monday, 16 May 4:00pm – 5:00pm

This seminar will be delivered in Online Zoom Please email chemistry.researchsupport@sydney.edu.au for zoom link and password.

Speaker: MS. Nuren Tasneem Natasha; The University of Sydney

Supervisor: Dr Yu Heng Lau

Title: Regulating self-assembly of megadalton-scale protein compartments

Abstract: Protein compartments are well-defined self-assembling architectures at the nanoscale. In nature, protein compartments enable spatial segregation and organisation of complex biochemical processes. These modular structures are also promising candidates for building chemical systems in vitro. In the past decade, chemists and bioengineers have used protein compartments as a tuneable scaffold for building nanoreactors and delivery vehicles. Central to these applications is the ability to regulate the process of self-assembly. Self-assembly regulation of protein compartments can allow for synthetic cargo to be encapsulated inside these highly engineerable systems and thereby enable the generation of innovative nanoscale platforms. In this seminar, I will discuss recent studies undertaken to control self-assembly of a class of protein compartments known as encapsulins.